van Amerongen Lab - Developmental, Stem Cell & Cancer Biology

- Swammerdam Institute for Life Sciences - University of Amsterdam -  

People

Staff


associate professor and group leader


Renée received her MSc from the Vrije Universiteit (1999, cum laude) and her PhD from the University of Amsterdam (2005, also cum laude). She did her PhD thesis research with Anton Berns at the Netherlands Cancer Institute and was a postdoc with Roel Nusse at Stanford University.
In 2013 she was appointed as MacGillavry fellow and tenure track assistant professor at the UvA. She was promoted to associate professor (with tenure) in 2017. Renée is an NWO VIDI laureate (2014) with more than 20 years of active research experience in Wnt signaling. She is also an elected member of the organizing committee of the European Network for Breast Development and Cancer labs and an editorial board member of the Journal of Mammary Gland Biology and Neoplasia. (complete CV here, updated 01/2021)


assistant professor

Thijs received his PhD from the Vrije Universiteit (VU university) in Amsterdam, where he worked on teratogenic effects of environmental pollutants on embryonic development. He did his postdoctoral research at Cancer Research UK and the Francis Crick institute in London in the lab of Caroline Hill. Here, he studied how embryonic signalling pathways control early development. As a research associate at Memorial Sloan Kettering Cancer Centre in Richard White’s lab he developed new models for pancreatic cancer. Thijs joined the lab in February 2021, bringing with him over 15 years experience at the crossroad of developmental and cancer biology.


technician

After obtaining an MSc degree at Leiden University in Molecular & Cellular Biology, Ingeborg started work as a technician in the lab of Vincent Christoffels at the Amsterdam University Medical Center (Amsterdam UMC) in April 2012. Focussing on development of the heart and cardiac repair after myocardial infarction, she performed molecular and in vivo work. Ingeborg joined the group in October 2020 as a technician, combining lab management support with experimental and technical support for ongoing research projects in the lab.





Postdocs & PhD students


PhD student

Yorick received his BSc from Utrecht University in 2013. In 2017 he obtained his MSc degree from the same university, after performing internships at the University Medical Center in Utrecht and at Stanford University (USA). He joined the group in February 2017 and works on identifying the mammary stem cell niche.


PhD student

In 2016 Saskia received her MSc degree (cum laude) from the University of Amsterdam, where she followed the track "Cell Biology and Advanced Microscopy". During her master she did an internship in the van Amerongen lab and went abroad for her second internship with Nadine Peyriéras (CNRS, Gif-sur-Yvette France). Saskia returned to the group to start a PhD in September 2016 and uses advanced microscopy techniques to further elucidate molecular mechanisms of Wnt signaling. This project is carried out in close collaboration with Dr. Mark Hink.


PhD student

Tanne received her BSc and MSc from the University of Amsterdam. She did her first BSc internship in the lab and later returned for a brief period as a guest researcher. During her MSc she performed internships at the Hubrecht Institute and in the lab of Chris Bakal at the ICR (London, UK). Tanne joined the lab in October 2019 as a PhD student and uses advanced microscopy techniques to further elucidate molecular mechanisms of Wnt signaling.





Current Wntlab students

Omayma Al-Qezweny, MSc internship (Biomedical Sciences, Developmental and Therapeutic Biology track)
February 2021 - August 2021
Research project: Tissue-specific regulation of WNT/CTNNB1 signaling

Omayma is performing her internship under the supervision of Renee and is using multiple online tools and existing datasets to generate new hypotheses regarding the regulation of Wnt5a and Wnt5b, which can be tested in the lab once the COVID-19 pandemic allows.

Jobana Ananthasabesan, MSc internship (Biomedical Sciences, Oncology track)
February 2021 - August 2021
Research project: Tissue-specific WNT/CTNNB1 signaling in the mammary gland

Jobana is performing her internship under the supervision of Renee and is using multiple online tools to investigate existing datasets to generate new hypotheses to be tested in the lab once the COVID-19 pandemic allows.

Jenny Heijkoop, MSc internship (Biomedical Sciences, Oncology track)
February 2021 - August 2021
Research project: Tissue-specific WNT/CTNNB1 signalling in the mammary gland

Jenny is performing her internship under the supervision of Renee and is using multiple online tools to investigate existing datasets to generate new hypotheses to be tested in the lab once the COVID-19 pandemic allows.

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Melanie Rietveld, MSc internship (Biomedical Sciences, Biochemistry and Biotechnology track)
February 2021 - August 2021
Research project: Functional imaging of CTNNB1

Melanie received her BSc from Amsterdam University College and is currently investigating the intracellular behavior of CTNNB1 under the supervision of Tanne van der Wal.

Zino Groen, Msc internship (Biomedical Sciences, Developmental and Therapeutic Biology track)
January 2020 - August 2020
Research project: Visualizing endogenous Wnt signaling in intestinal organoids

Zino's research internship (under the supervision of Yorick) was brutally interrupted by the COVID-19 pandemic. While the lab was closed, he wrote his literature thesis on lineage tracing in the mammary gland under the supervision of Renee.